TURMERIC MAY BE USEFUL IN TREATING ALZHEIMER’S
Turmeric has been used in Ayurveda to treat numerous diseases for over 5,000 years. It possesses anti-amyloidogenic, anti-oxidative, and anti-inflammatory properties. Curcuma is a polyphenolic compound derived from the plant Curcuma Long Lin that has been demonstrated to have antioxidant and anti-inflammatory effects as well as effects on reducing beta-amyloid aggregation. It reduces pathology in transgenic models of Alzheimer’s disease (AD) and is a promising candidate for treating human AD.
Various research have previously indicated a lower incidence and prevalence of AD in India, with a prevalence of AD among adults aged 70-79 years in India is 4.4 times less than that of adults aged 70-79 years in the United States.
Research has shown that AD degrades the nerve cells is believed to involve certain properties: inflammation, oxidative damage and most notably, the formation of beta-amyloid plaques, metal toxicity. Possible mechanism of Turmeric are:
• Help the macrophages to clear the amyloid plaques
• Curcumin has anti-proliferative actions on microglia
• Acts as an anti-inflammatory in AD
• Curcumin inhibits the activity of AP-1, a transcription factor involved in expression of amyloid, which is linked to AD
• Levels of beta-amyloid in AD mice that were given low doses of curcumin were decreased by around 40%
Diabetes itself increases the risk of dementia 2-3-fold.A recent small controlled study (Asia Pac J Clin Nutr 2014;2 ) has found that taking ½ teaspoon of Turmeric with nutritionally-bland breakfast resulted in improvements in short-term memory in people over the age of 60 who were diagnosed with pre-diabetes. The breakfast used was not typical for the population. The study used soft-white bread, as the first meal of the day, especially among elderly people with chewing difficulties and also its nutritional profile was restricted.
Turmeric, the traditional Indian culinary herb, yellow on account of its curcumin pigment, can thus improve post-prandial working memory in people with pre-diabetes who are prone to cognitive impairment. The researchers further stated that it does this independently of body fatness, insulin resistance and known biomarkers of Alzheimer’s disease pathogenesis, its efficacy is dependent on energy balance and insulin status. Many CAM Practitioners advocate the use of turmeric inclusion in one;s diet, so why not try adding turmeric to food.
Here are some suggestions:
Add a pinch of turmeric in scrambled eggs, or tofu scramble. Also you can add a small onion, cumin and season with salt.
Add a dash of turmeric to basmati rice with a little salt for delicious tasting rice.
Smoothies and fruit juices
Add a little turmeric root to fresh juices and smoothies
Roasted Cauliflower with cumin and turmeric
Add ¼ tsp of turmeric powder with cumin and olive oil. Cook on low heat and garnish with fresh coriander and season with salt
Simmer milk or soy milk with ½ tsp on turmeric and dry ginger. Use honey when milk is cooled down to sweeten if required.